Familiarize yourself with the 2D View for vector drawing and the 3D View for visualizing reliefs and toolpaths. Design Fundamentals: Vectors and Reliefs
Set your material dimensions (height, width) and resolution. Higher resolution is better for complex reliefs but takes more processing power.
Use Z-Level Roughing to quickly remove bulk material, followed by Relief Machining for the final detail.
Always run a Toolpath Simulation before exporting. This lets you visualize the finished product and catch errors without wasting material. Pro Tips for Efficiency Autodesk ArtCAM 2018 - Getting Started
ArtCAM is unique because it blends 2D drawing with 3D sculpting.