You are reacting (S)-2-phenylpropanal with methylmagnesium bromide (MeMgBr). Task: Use the Felkin-Anh model to predict the major diastereomer formed. Draw the transition state and explain why the nucleophile attacks from a specific face. Problem 2: Pericyclic Mechanisms
Test your knowledge with these representative advanced problems. (Solutions are discussed conceptually below). Problem 1: Predicting the Diastereomer advanced organic chemistry practice problems
In my synthesis, am I using the most efficient route, or am I adding and removing protecting groups unnecessarily? Recommended Resources for Further Practice advanced organic chemistry practice problems